Molybdenum-99 (99Mo or “moly”)

Molybdenum-99 is the parent isotope of technetium-99m (99mTc), a light-emitting element that is administered to some 55,000 Americans every day for the purpose of diagnosing and staging a multitude of diseases, including cancer and heart disease.

SHINE Medical Technologies will produce 99Mo, which is loaded into Technetium-99m generators. As 99Mo turns into 99mTc within the generator, the 99mTc can be extracted by radiopharmacy staff for use in patients. In fact, 99mTc is used in over 80% of nuclear diagnostic procedures worldwide, and thus lies at the heart of modern nuclear medicine.

Diagnostic medical procedures using 99mTc. Myocardial perfusion studies are typically done to diagnose and stage heart disease. Bone scans are typically performed for cancer staging. (Click image to enlarge)


Iodine-131 (131I)

Iodine-131 is widely used to treat thyroid cancer and other abnormal thyroid conditions, such as hyper-thyroidism (an over-active thyroid). It is also used to diagnose liver function, renal (kidney) blood flow and urinary tract obstruction.


Iodine-125 (125I)

Iodine-125 is used in a type of cancer therapy known as brachytherapy, in which small sealed sources are placed inside or next to the area of treatment. It is commonly used in the treatment of prostate cancer and brain tumors. It is also used diagnostically to evaluate kidney function and diagnose deep vein thrombosis in the leg.


Xenon-133 (133Xe)

Xenon-133 is inhaled as a gas to evaluate regional function in emphysema and other forms of chronic and obstructive lung disease. It can also be used to image blood flow, particularly in the brain.