Moly-99 Production Demo

Argonne National Laboratory (Argonne) successfully demonstrated the production, separation, and purification of molybdenum-99 (Mo-99) from SHINE’s innovative liquid target. The resulting Mo-99 product purity was equivalent to the Mo-99 used in the supply chain today. The demonstration—known as Mini-SHINE— uses the same process flows that will be used in the SHINE manufacturing facility and further validates SHINE’s technical approach.

Earlier tests performed by Los Alamos National Laboratory found near-complete recovery of the Mo-99 from SHINE’s liquid target, and that this yield did not change when the target solution was recycled.

Argonne took testing of the liquid target a step further by building a tip-to-tail pilot demonstration. The Mini-SHINE test validates every step of the production chemistry: from plant – relevant irradiation conditions through purification of the Mo-99 to current industry standards.  The work was supported by the Department of Energy’s National Nuclear Security Administration’s Mo-99 Program.